Top Downtown Greenville Hotels

We checked thousands of reviews on and to find the best hotels for your stay
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Jacob Smith

Updated: 02 August 2024 · 4 min

Welcome to the vibrant and dynamic city of Greenville, located in the beautiful state of South Carolina. Known for its charming downtown area, Greenville offers a plethora of accommodations ranging from boutique hotels to luxury stays right in the center of the action. With a bustling culinary scene, thriving arts community, and stunning natural landscapes, choosing to stay in downtown Greenville ensures you are at the epicenter of all the excitement.

Immerse yourself in the Southern hospitality and unique charm that Greenville hotels downtown have to offer. From stylish boutique hotels that cater to the design-conscious traveler to historic inns brimming with character, there is a perfect accommodation option for every type of visitor. Explore the picturesque Falls Park on the Reedy River, dine at award-winning restaurants, and soak in the vibrant energy of downtown, all just steps away from your hotel.

Whether you are visiting for business or leisure, staying in one of the many downtown Greenville hotels provides easy access to top attractions, shopping districts, and entertainment venues. Discover the convenience of walking to popular landmarks such as the Peace Center, the Greenville Zoo, and the Swamp Rabbit Trail, all while enjoying the comfort and luxury of your centrally located hotel. Experience the best of Greenville right at your doorstep.
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Our Top 7

(Sorted by rating & number of reviews)

1. Days Inn By Wyndham Greenville
2. Quality Inn & Suites Greenville I-65
3. Comfort Inn Greenville I-65
4. Best Western Greenville Inn
5. Holiday Inn Express Hotel & Suites Greenville, An Ihg Hotel
6. Hampton Inn - Greenville
7. Baymont By Wyndham Greenville

Luxurious Getaways at Greenville Hotels Downtown

Check Availability

Greenville
Mar 23, 2026 - Mar 24, 2026

Days Inn By Wyndham Greenville

6.6

Good

(78 Reviews)

+ 34 photos
The Days Inn by Wyndham Greenville provides a budget-friendly option for travelers seeking a comfortable stay in downtown Greenville without compromising on quality. Offering well-appointed rooms, complimentary breakfast, and a seasonal outdoor pool, this hotel caters to guests looking for a relaxed and affordable accommodation option. Its location near downtown restaurants and shopping makes it a convenient choice for those wanting to experience the vibrant city life of Greenville.
Address: 946 Fort Dale Rd
Rating: Good 6.6 (78 Reviews)
Rooms: 39
Price: From 77$

Quality Inn & Suites Greenville I-65

6.5

Good

(218 Reviews)

+ 72 photos
The Quality Inn & Suites Greenville I-65 stands out as a luxurious retreat in downtown Greenville, offering spacious rooms and suites with modern amenities. Guests can relax in the outdoor pool or unwind in the fitness center before exploring the nearby attractions, including Falls Park on the Reedy River and the Peace Center. With its convenient location and upscale ambiance, this hotel provides a perfect blend of comfort and sophistication for travelers seeking a refined stay in the very heart of Greenville.
Address: 941 Fort Dale Road
Rating: Good 6.5 (218 Reviews)
Rooms: 86
Price: From 82$

Contemporary Comfort at Greenville Hotels Downtown

Modern travelers seeking a blend of style and comfort will find an array of contemporary hotels in downtown Greenville that cater to their aesthetic preferences and practical needs. These hotels offer sleek and sophisticated accommodations with state-of-the-art amenities, perfect for those looking for a chic urban retreat in the lively heart of the city. Whether visiting for business or pleasure, guests can enjoy a seamless stay in these trendy and convenient downtown establishments.

Comfort Inn Greenville I-65

8.3

Good

(253 Reviews)

+ 110 photos
The Comfort Inn Greenville I-65 provides a welcoming retreat for guests seeking a cozy and inviting atmosphere in downtown Greenville. With spacious rooms, a complimentary hot breakfast, and a business center, this hotel caters to both leisure and business travelers. Its prime location allows guests to easily access downtown landmarks, shopping areas, and entertainment venues, making it an ideal choice for those wanting to experience the best of Greenville while enjoying a comfortable stay.
Address: 1029 Fort Dale Rd
Rating: Good 8.3 (253 Reviews)
Rooms: 54
Price: From 97$

Best Western Greenville Inn

7.8

Good

(285 Reviews)

+ 50 photos
The Best Western Greenville Inn exudes a classic charm with its elegant decor and personalized service, making it a popular choice for visitors looking for a comfortable stay in downtown Greenville. The hotel features well-appointed rooms, a complimentary breakfast buffet, and a fitness center, ensuring guests have everything they need for a relaxing stay. Situated close to downtown attractions and dining options, this hotel offers a blend of convenience and luxury for travelers exploring Greenville.
Address: 56 Cahaba Road
Rating: Good 7.8 (285 Reviews)
Rooms: 45
Price: From 135$

Cozy Retreats at Greenville Hotels Downtown

For travelers seeking a more intimate and inviting stay, downtown Greenville boasts several cozy hotels that provide a warm and welcoming atmosphere for guests looking for a home-away-from-home experience. These charming accommodations offer personalized service, homely decor, and a sense of tranquility amidst the bustling city, making them ideal for those seeking a peaceful and relaxing retreat in downtown Greenville.

Holiday Inn Express Hotel & Suites Greenville, An Ihg Hotel

9.2

Good

(192 Reviews)

+ 82 photos
The Holiday Inn Express Hotel & Suites Greenville, an IHG hotel, presents a contemporary and stylish setting for guests looking for upscale accommodations in downtown Greenville. Featuring spacious rooms, a complimentary hot breakfast, and a 24-hour fitness center, this hotel ensures a comfortable and convenient stay for travelers. With its modern design and proximity to downtown attractions, this IHG hotel offers a perfect combination of comfort and sophistication for guests exploring Greenville.
Address: 100 Paul Stabler Drive
Rating: Good 9.2 (192 Reviews)
Rooms: 67
Price: From 145$

Hampton Inn - Greenville

8.5

Good

(64 Reviews)

+ 86 photos
The Hampton Inn - Greenville greets guests with its cozy ambiance and friendly service, offering a comfortable haven in downtown Greenville. With spacious rooms, a complimentary hot breakfast, and a fitness center, this hotel provides a relaxing stay for both leisure and business travelers. Its central location allows guests to easily explore downtown attractions such as the Greenville County Museum of Art and the Swamp Rabbit Trail, making it a convenient choice for travelers seeking a cozy retreat in the center of the city.
Address: 219 Interstate Drive
Rating: Good 8.5 (64 Reviews)
Rooms: 69
Price: From 116$

Baymont By Wyndham Greenville

6.4

Good

(56 Reviews)

+ 40 photos
The Baymont by Wyndham Greenville offers a charming escape for guests looking for a cozy and inviting stay in downtown Greenville. Featuring well-appointed rooms, a complimentary breakfast, and a seasonal outdoor pool, this hotel provides a relaxing oasis in the lively heart of the city. Its proximity to downtown dining and shopping destinations makes it a convenient choice for travelers wanting to experience the warmth and hospitality of Greenville in a comfortable setting.
Address: 71 Jameson Ln
Rating: Good 6.4 (56 Reviews)
Rooms: 41
Price: From 65$